2024
Antibody dynamics against specific T.cruzi antigens in patients undergoing chemotherapeutic treatments
Abstract Currently available first-line antiparasitic treatments against Chagas disease can produce adverse side effects and are not …
2022
Development of a Chagas Disease Antigen and Epitope Atlas using massively parallel serological assays
How we used peptide arrays to discover new antigens and epitopes and map the presence of antibodies in patients
2022 SAP A drug-target prioritization strategy using the TDR Targets database leads to novel trypanocidal compounds with known active functional groups
Only got two mins? The drug repurposing approach to drug discovery for neglected diseases has shown to be effective to find potential …
2019
The serological antibody repertoire in Chagas Disease
Towards a comprehensive description of the specificities of individual antibody repertoires in Chagas Disease
TDR Targets: driving drug discovery for human pathogens through intensive chemogenomic data integration
Mind the gap: Bridging the knowledge rift between model organisms and pathogens causing neglected diseases
From yeast to tryps: repurposing strategies through conserved druggable modules
Computational repositioning of bioactive compounds from large chemogenomic screens: identification of conserved druggable modules …
2018
Discovery and fine epitope mapping of novel serology-based markers for diagnosis of Congenital Chagas Disease using high-density peptide chips
How we use this technology to discover new antigens and epitopes in matched mother-newborn samples
TDR Targets: integrated chemogenomic mining of pathogen genomes for drug discovery
A recap on updates & updagrades for TDR Targets chemogenomics resource to aid on drug discovery, repurposing and develeopment for …